Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis and can affect many organs. Infection with Mycobacterium tuberculosis does not always cause morbidity in humans, but may cause clinical morbidity when resistance is reduced or cell-mediated metaplasia is increased. Most of them can be cured clinically if they are diagnosed in time and treated appropriately. Mycobacterium tuberculosis belongs to the order Actinomycetes, Mycobacterium genus has pathogenic acid-resistant bacteria, mainly divided into human, bovine, bird, mouse and other lines, pathogenic to humans are mainly human type bacteria, bovine type bacteria rarely infected. Resistance of Mycobacterium tuberculosis to drugs can be developed by the development of innately resistant bacteria in the flora; it can also be due to the use of an anti-tuberculosis drug alone in humans, and resistance to the drug can develop relatively quickly.