1. Do I have to use medication for pediatric epilepsy? Whether to start antiepileptic drug treatment after the first seizure in children needs to consider the cause of epilepsy, seizure type, epilepsy syndrome, etc. For example, after the first cluster seizure in benign infantile epilepsy, antiepileptic drugs can be temporarily not used and continue to be observed, and then start treatment with antiepileptic drugs if there is a 24-hour interval between seizures again. For example, children with benign epilepsy with spikes in the central temporal region with a long interval of recurrence are not necessarily in a hurry to use antiepileptic drugs, and even some children have only 1-2 seizures in their lifetime, and overtreatment of such children will do more harm than good. 2. What will be the outcome if I don’t take medication? Overall epilepsy needs to be diagnosed and treated early. This is because repeated multiple seizures, especially prolonged full-blown seizures, may damage brain function and may further affect normal brain development in developing pediatric patients. For some severe epileptic syndromes, such as infantile spasms, it is even more important to control epileptic activities as soon as possible, only in this way can the harm caused by epileptic activities be reduced as much as possible. 3, at present, the treatment of pediatric epilepsy drugs, which are the main kinds? At present, the traditional anti-epileptic drugs commonly used in China are: carbamazepine (CBZ), phenobarbital (PB), valproic acid (VPA), clonazepam (CZP), phenytoin sodium (PHT); new anti-epileptic drugs are: lamotrigine (LTG), levetiracetam (LEV), oxcarbazepine (OXC), topiramate (TPM). 4. In general, should I take one drug or a combination of drugs? Generally, with the rational application of one antiepileptic drug, the control rate of epilepsy can reach about 60% to 70%. Monotherapy has the following advantages: easy to judge drug efficacy and adverse effects; no drug interactions; relatively few adverse effects; simple program and good compliance; and light economic burden. For patients who have switched to two or three antiepileptic drugs and still cannot control their seizures after the dose and blood concentration have reached a high level or have multiple seizure types that are predictive of refractory epilepsy, an appropriate combination of drugs can be administered. The more types of drugs used in combination, the more complex the interactions. It is recommended that two to three drugs be used in combination therapy. 5. How long do I need to take medication in general? Is it possible for some children to stop medication at puberty? After antiepileptic drug treatment, about 60% to 70% of epileptic patients can achieve seizure-free. Usually, patients on antiepileptic medication who have been seizure-free for more than two years have the potential to reduce their medication; for those with structural brain abnormalities or some specific syndromes (such as JME) this should be extended to 3-5 years seizure-free. For a few age-related epilepsy syndromes (e.g., BECT), drug reduction can be considered beyond the age of disease.