Breast cancer patients are most worried about tumor recurrence after surgery, but how to determine their chances of recurrence has always been a confusing issue, now we provide the latest International Breast Cancer Research Organization’s criteria for grading the risk of breast cancer recurrence as follows: 1. 2. Moderate risk: lymph node negative with at least one of the following: 1, lesion size (pT) ≥ 2 cm or 2, grade 2-3 or 3, peritumoral vascular tumor invasion or 4, HER-2 gene overexpression or amplification or 5, age <35 years< span=""> 6, positive lymph nodes 1 – 3 and no HER2 -3. High risk: 1, 1-3 positive lymph nodes with HER2 overexpression or amplification 2, ≥4 positive lymph nodes