The interval between medications is mainly related to the half-life of the medication and the metabolism rate of the patient’s liver and kidney function, and the half-life of different medications is different, so the interval between medications is also different. In case of hepatic or renal insufficiency, the dosage and interval between doses should be adjusted according to the doctor’s instructions. Different drugs have different pharmacokinetics, that is, different drugs have different metabolism time in the body and different half-lives. Generally speaking, medication should be taken in accordance with the drug instructions or medical advice, such as once a day, which is 24 hours apart, twice a day, which is 12 hours apart, and three times a day, which is 8 hours apart. The medication should be taken in strict accordance with the instructions or medical advice, and during the period of taking the medication, the consumption of spicy and stimulating food should be reduced, and attention should be paid to rest, nutrition and exercise.