It is true that the incidence of mastocytosis is very high, with some data saying that it is over 50%, but this should not be taken lightly. Because mastocytosis is a precancerous disease, 20% of breast cancers are combined with mastocytosis, and 3-5% of mastocytosis have the possibility of cancer. In recent years, the incidence of breast cancer has surpassed that of uterine cancer and cervical cancer, threatening the lives of many women, so we should all pay attention to the treatment and examination of mastocytosis. Treatment of mastocytosis: 1. Regular checkups for early detection and timely treatment. 2. 2.Adherence to medication The disease is a serious endocrine disorder, the lesion tissue has poor sensitivity to drugs, the lumps disappear slowly, and the treatment time is long, sometimes it takes six months to a year for internal medication to take effect. 3.Surgical total excision is the best treatment for localized lesions, i.e., as long as the large local lesions are removed, the treatment effect is mostly positive. If there is an obvious tendency of cancer, or if it is diagnosed as precancerous lesion by biopsy, simple mastectomy should be performed to be safe. In addition, when patients have breast overflow, they should be distinguished from hyperprolactinemia or amenorrhea breast overflow syndrome to prevent misdiagnosis.