Most colds are associated with generalized malaise and malaise, and most colds do not cause fever. In contrast, in addition to general malaise, novel coronavirus infection has more respiratory symptoms, such as dry cough, shortness of breath, dyspnea, and even acute respiratory distress syndrome and blood clotting disorder in severe cases. Secondly, the infectious ability of cold is much smaller than that of novel coronavirus. During the incubation period of novel coronavirus infection, the patient already has the ability to infect others, so isolation and self-protection are extremely important during the novel coronavirus outbreak.