Patients with tethered cord syndrome, especially children, should be alerted to one clinical manifestation of the disease: hairy, abnormally pigmented skin in the lumbosacral region. Tethered cord syndrome (TCS) is a syndrome in which the spinal cord or conus is stretched due to various congenital and acquired causes, resulting in a series of neurological dysfunctions and deformities. TCS is also known as hypospadias because the spinal cord is mostly stretched in the lumbosacral medulla, causing the cone to be abnormally low. Prevention and care of lumbosacral skin hirsutism and abnormal pigmentation: (1) Do psychological care and do skin care locally for patients with skin breakdown. (2) Take the lateral position after surgery to prevent local pressure, and prone position for those with cerebrospinal fluid leakage. (3) Paralyzed patients closely observe the lower limb muscle strength, often out of the lower limb muscle strength is weakened, mild muscle atrophy, numbness, urine loss onset, with the development of the disease performance of lower limb movement disorders. Assist the patient to turn over and prevent the formation of le sore. Assist in functional exercise of the limbs to prevent disuse atrophy and deformity. (4) Neurotrophic changes are common when the lower limbs are obviously hypotonic, manifesting as freezing, spasm, ulcers in the distal part of the lower limbs, and can tail are also often seen. Care should pay attention to the correct use of hot water bags and ice packs to prevent burns and frostbite. Turn over regularly to prevent local pressure. Follow the doctor’s instructions to make the foundation neurotrophic drugs, trauma local drug changes 1-2 times a day. (5) Cerebrospinal fluid leakage is often caused by fracture of the middle fossa of the skull involving the tympanic chamber, because the rock bone is located at the junction of the middle and posterior fossa of the skull, and blood cerebrospinal fluid can enter the tympanic chamber as long as the middle fossa part or the posterior fossa part of the rock bone is fractured. If the eardrum is ruptured, the cerebrospinal fluid may flow out through the external ear canal, while when the eardrum is intact, the cerebrospinal fluid may flow to the pharynx through the Eustachian tube or even return from the posterior nasal aperture to the nasal cavity and then overflow from the nostril, which is similar to the nasal leakage caused by the fracture of the anterior fossa and is easy to be misdiagnosed.