Tetanus is often associated with trauma, especially after a deep wound or a rusty nail, and the patient should be given tetanus antitoxin as soon as possible, preferably within 24 hours. The purpose of tetanus antitoxin is to neutralize the free toxin, so it is effective only when applied at an early stage, and it is difficult to be effective if the virus has already combined with the nerve tissue. For those who can find the wound, a thorough debridement should also be performed at the first opportunity to remove foreign bodies and necrotic tissue, and if necessary, incision and drainage. In addition, newborns should be injected with the tetanus combination vaccine in the 3rd, 4th and 5th months after birth, and then given a booster immunization at the age of 1.5 to 2 weeks, which has a better effect on the prevention of tetanus, and the antibodies can be maintained for a period of 10-15 years. Since tetanus is an extremely serious disease with a high mortality rate, people need to take precautions and get tetanus antitoxin injections as early as possible.