1, polluting gas inhalation: such as smoking, long-term inhalation of second-hand smoke, or inhalation of polluting gases containing sulfur dioxide, soot, lime, etc., some of the particles in the gas are directly inhaled into the lungs, on the one hand, impairing lung function, on the other hand, causing secondary infections. When the alveolar tissue exudate, tissue debris and other accumulation, with coughing sputum, part of the deposition of particles with the sputum discharge, there can be a small brown jelly-like clots. At this time, it is necessary to get out of the polluted environment as soon as possible, and if necessary, give cefoperazone sodium and other anti-infective treatment, and at the same time with the sputum treatment with drugs such as aminoglutethimide hydrochloride to promote sputum discharge and polluting particles deposition; 2, Klebsiella pneumoniae infection: Klebsiella pneumoniae is a normal presence of bacteria in the environment, but also in the oral pharynx can be colonization, can be mistakenly inhaled along with secretion when the body’s immune system is impaired, which leads to pulmonary Infection. A small number of patients may acquire it nosocomially, such as being infected after using a nebulizer that has not been properly sterilized, but it tends to develop in clusters and may often lead to severe lung infections with the potential for multi-drug resistance. Typical symptoms are sputum that is brown and jelly-like in nature, with alcoholism being the main trigger, and fever, chills, cough and sputum. Patients need to improve the sputum culture to identify the infectious agent, and the chest radiograph usually shows lobular solid changes, lobular infiltration, and abscess formation. Treatment can choose β-lactam antibiotics, such as ampicillin, or directly give ceftazidime and other third-generation cephalosporins. Severe cases are given aminoglycoside or quinolone antibiotics active anti-infective treatment, such as common streptomycin, gentamicin sulfate, ciprofloxacin hydrochloride, etc., as well as giving aminoglycoside hydrochloride and other drugs, sputum chemotherapy; 3, respiratory infections: including acute sinusitis, pharyngolaryngitis, and tracheal or bronchial inflammation, etc., when there is a postnasal drip leakage of secretion, or because of inflammation damage to the bronchial mucosa, resulting in mucosal congestion and edema. Increased permeability of the bronchial capillary walls and oxidized hemoglobin are present in the sputum, resulting in small brown jelly-like clots in the sputum. Antiinfective treatment with penicillin and ceftriaxone sodium is usually required for infectious diseases, and the nature of the sputum may improve after the infection is controlled.