The difference between liver coarsening and diffuse hepatic lesions in ultrasound findings is that diffuse hepatic lesions are commonly associated with extensive liver damage, whereas liver coarsening and enhancement suggests imaging changes caused by localized hepatic lesions. 1. Thickening of liver echoes refers to pathological damage to the liver, resulting in necrosis of liver cells, and fibrosis of the liver due to the protective mechanism of the body. Fibrotic liver tissue is denser than normal liver tissue, so it will show thickening of echoes and enhancement of the problem. 2. Diffuse lesions of the liver are relative to focal lesions, such as cirrhosis and fatty liver are diffuse lesions Diffuse lesions are commonly found in hepatitis B, hepatitis C, fatty liver, alcoholic liver, and drug-related liver damage. Any abnormal changes in the liver detected by ultrasound should be promptly treated in a regular hospital for further diagnosis and treatment.