Pain is a complex phenomenon in medical science, because it can be a symptom or a disease; it is widespread, because everyone in the world experiences it to varying degrees, regardless of gender, age, or age. At the same time, pain is a major social and economic problem, because various kinds of pain require longer consultation and treatment, which not only hinders work but also costs a lot of medical expenses, and is one of the problems worthy of attention from all walks of life. Modern pain research findings suggest that pain itself is a type of disease. Acute and chronic pain leads to deregulation of the nervous system at the molecular, cellular, psychological and social levels. We need to improve the control of all types of pain at an early stage so as not to transform it into long-term, chronic pain, which leads to dysfunction of the organism and reduced quality of life. The purpose of modern pain treatment is to adjust, support and rehabilitate the abnormal human nervous system from multiple levels of physiological, psychological, behavioral and social adaptations. Acute pain 1, trauma pain Various traumatic factors that can cause tissue damage to the body can lead to different degrees of pain, which occupies a large proportion of the acute pain range in surgery, this traumatic pain often presents a continuous pain nature, intensifies when the activity, the degree of pain is moderate to severe. 2, burns, scalding pain burns, scalding is a special type of traumatic pain, it is caused by flame, boiling water and strong acid, alkali caused by the body surface Ⅰ-II degree of injury, pain is continuous, the degree of more intense. 3.Inflammatory pain The bacterial or viral infectious process of different tissues and organs can also cause pain of different degrees, which also occupies a large proportion of the pain process in the field of surgery, which is mostly persistent and hidden pain, but can also be accompanied by paroxysmal pain, and the degree is mild to moderate. 4, nerve stimulation or compression pain due to herniated disc compression or nerve roots, non-infectious inflammation of the tissue around the stem and other pathological processes of stimulation can produce spontaneous pain, the nature of this type of pain such as knife, lightning or tear-like pain, the degree of intense, the patient can not tolerate. 5.Postoperative pain Mainly due to the trauma of surgical incision, damage to internal organs and stimulation and irritation of drainage materials resulting in immediate postoperative pain, this type of pain belongs to acute pain, and the degree is also more intense, especially during the 48 hours after surgery, which is often one of the main causes of postoperative complications and affects the recovery of postoperative patients. And factors such as postoperative scar tissue, damage to nerves and adhesions of the thoracic and peritoneal membranes are the reasons for prolonged postoperative pain. 6.Late stage tumor pain Most of the tumor pain is caused by the compression and infiltration of the tumor itself or the metastasis of nearby tissues, other organs and systems. This pain is persistent and hidden at first, and progressively intensifies with time, and the pain is mildly intense at the later stage, which makes the patients restless and sleepless, and the quality of life is extremely low. 7, special treatment pain abortion, fiberoptic gastroscopy and/or colonoscopy accompanied by pain or uncomfortable feeling. Chronic pain: pain caused by long-term strain or degenerative changes in joints, soft tissues (muscles, fascia, ligaments, etc.); 2. 4.Tumor-related pain: pain caused by the growth of the tumor itself, compression or local or invasive changes to adjacent tissues due to metastatic tumors; 5.Immune-related pain: pain caused by various factors related to changes in immune mechanisms; 6.Ischemic pain: pain caused by reduced blood supply; 7.Bruising pain: pain caused by vascular factors or blood flow disorders; 8.Bruising pain: pain caused by the loss of blood supply. 8. mental and emotional pain: various pains caused by depression or anxiety disorders, sub-health states, drastic or obvious emotional changes, etc. 1.Patients with pain should go to the pain department, neurology department, orthopedics department, rehabilitation department, oncology department and other outpatient clinics in regular hospitals, as the general acute and chronic pain can be controlled timely and satisfactorily; 2.At least three consecutive outpatient visits to make an evaluation, because even the most brilliant doctors cannot solve the problem or play an obvious therapeutic effect in one visit; 3.Bring the complete medical records and examination data 4.Tell the doctor the real condition and cooperate with him/her in every examination and treatment; 5.Feedback the reaction after taking the medicine in time and consult at any time if you do not understand the problem.