Trigeminal neuralgia is a common disease that is highly prevalent in the middle-aged and elderly population. It is often manifested by recurrent episodes of severe pain in the distribution area of the trigeminal nerve on one side of the face, which can occur due to washing, talking, brushing teeth, or even walking or breezing, seriously affecting the physical and mental health as well as the work and life of patients. With such unbearable and severe pain, patients are basically treated actively, but due to the lack of sufficient knowledge about the disease, many patients suffer from wrong treatment. What are the diseases that trigeminal neuralgia can easily be treated wrongly? 1. toothache: trigeminal neuralgia is most easily mistaken for toothache at the beginning, and some patients even have their teeth extracted. So how to distinguish trigeminal neuralgia from toothache? In fact, the method of differentiation is very simple. The suddenness of trigeminal neuralgia is very strong and can be said to be lightning-like pain, but the performance of toothache is a persistent and strong bout of pain. 2. Migraine: People often have migraine headaches, which basically occur in young women and are painful around the orbital and frontotemporal areas. And there are three branches of trigeminal neuralgia, namely the ophthalmic branch, the maxillary branch and the mandibular branch, of which the ophthalmic branch is most easily confused with migraine. The distinction is that trigeminal neuralgia is paroxysmal, with sudden onset and stop, pain lasting seconds or minutes, the presence of trigger points, and can be triggered by touching. 3. Glossopharyngeal neuralgia: Glossopharyngeal neuralgia is uncommon, but it is also very easy to confuse with trigeminal neuralgia. From the point of view of glossopharyngeal neuralgia, the main characteristic is that there is a kind of intense pain when swallowing, but no disease appears at other times, and trigeminal neuralgia is highly prevalent in people over 40 years of age, while glossopharyngeal neuralgia is mostly prevalent in people of 40 years of age. In the treatment of trigeminal neuralgia, only a clear diagnosis and correct treatment can relieve the patient’s pain. Patients cannot tell the difference and should seek medical attention promptly, the disease is a neurological disease and patients consult neurology or surgery. Trigeminal neuralgia can be effectively relieved by taking carbamazepine or oxcarbazepine drugs. For a few patients who cannot tolerate the side effects of medication, or for severe patients who do not take medication well, surgical treatment can be considered. Some patients have secondary trigeminal neuralgia with a clear cause. There are also patients with pain without obvious causes. According to clinical research, these patients are mostly caused by pulsatile compression of the trigeminal nerve root into the pontine brain by intracranial blood vessels. According to this rationale, clinical treatment with manifest microvascular decompression, which is less invasive and does not damage the nerves, can achieve a cure.