Novel coronavirus infections have the potential to heal spontaneously. The vast majority of people infected with the virus have mild symptoms, exhibiting only low-grade fever, dizziness, nasal congestion, and mild malaise, with no signs of secondary pneumonia. Patients who are admitted to the hospital need only proper isolation and rest as well as symptomatic treatment, and will recover on their own after a week. After admission, a small number of seriously ill patients should be admitted to the hospital, bed rest, strengthen supportive therapy, ensure adequate nutrition and heat; at the same time, pay attention to their water-electrolyte balance, and regularly monitor blood and urine routine, biochemical indicators and coagulation function, etc., and give appropriate oxygen therapy when necessary. Currently, the clinical trial of α-interferon nebulized inhalation or oral lopinavir/ritonavir has some therapeutic effect on some patients.