Etiology: 1, local tissues are repeatedly used, resulting in tissue damage and not timely repaired; 2, systemic diseases caused by abnormal tension and spasm of local tissues; 3, due to environmental temperature changes caused by local vascular spasm, the circulatory system nutrient supply decline, local metabolite accumulation; 4, long-term, repeated, continuous repetition of the same posture, work, study and occupational movements, beyond the body’s local compensation 5, unskillful technique, inattention and incorrect posture in operation, which can produce abnormal stress locally; 6, abnormal body physiological structure, uneven distribution of stress; 7, failure to get correct rehabilitation after acute injury, which turns into chronic injury. Clinical features: 1, long-term local chronic pain, but no clear history of trauma; 2, a pressure point or mass in a specific area, often accompanied by some special signs; 3, no obvious acute inflammation in the local area; 4, a recent history of excessive activity related to the pain site; 5, some patients have a history of postures, work habits or occupations that can lead to chronic injuries of the locomotor system. Treatment principles: 1, this disease is caused by long-term poor posture, posture and occupational local damage, limit the injury-causing movements, correct poor posture, enhance muscle strength, maintain joints non-weight-bearing activities and timely change of posture so that stress dispersion, thereby reducing the injurious factors, increase protective factors is the key to treatment, otherwise it is easy to relapse. 2, physiotherapy, massage and other physical therapy can improve local blood circulation, reduce adhesions, help improve symptoms. Local creams can be used, but also after applying topical non-steroidal anti-inflammatory drugs live herbal preparations, repeated gentle massage to increase its skin permeability and reduce the local inflammatory response. 3.Rational application of non-steroidal anti-inflammatory drugs (celecoxib, erliximab, etoricoxib, loxoprofen, ibuprofen, etc.). Non-steroidal anti-inflammatory drugs have obvious efficacy in reducing or eliminating local inflammation, and can be used intermittently for a short period of time, but long-term use will have different degrees of adverse reactions, including gastrointestinal mucosal damage is most common, followed by liver and kidney damage. Attention to the use of: (1) short-term use; (2) lesions limited and superficial use of non-steroidal anti-inflammatory drugs in topical dosage form; (3) in order to reduce the damage to the gastrointestinal tract, selective cyclo-oxygenase 2 (COX-2) inhibitors (eg, celecoxib, erexib, etoricoxib, etc.), precursors and a variety of slow-release agents, enteric tablets, suppositories, and so on, you can also add the use of non-steroidal anti-inflammatory drugs in the application of non-steroidal anti-inflammatory drugs at the same time Gastric mucosal protective agent; (4) for renal insufficiency can choose short half-life, less impact on renal blood flow of drugs; (5) in order to reduce the impact on liver function, can choose a simple structure, no nitrogen-containing drugs, to avoid the use of indomethacin and aspirin; (6) NSAIDs can not be a variety of combined, or anti-inflammatory analgesic effect does not increase rather than increase the adverse effects. 4, closed treatment (adrenal glucocorticoid). Attention should be paid to the fact that it cannot be used repeatedly, otherwise it will cause tendon and ligament degeneration (for example, the Achilles tendon rupture of Liu Xiang); patients with poor physique and high blood sugar are easy to be infected. When using, pay attention to: (1) diagnosis of chronic injury inflammation, not bacterial inflammation or tumor; (2) strict aseptic operation; (3) accurate injection site, to avoid accidental entry into the blood vessels and nerves; (4) according to the prescribed dosage and method; (5) be alert to infections after injection. (5) Adopt surgical treatment when appropriate.