Stroke is characterized by high morbidity and disability, and about 2 million people suffer from stroke every year in China, among which 11% to 55% of stroke patients suffer from chronic pain, such as musculoskeletal pain, shoulder pain, painful spasms, headache, and post-stroke central pain, etc. The medical treatment of post-stroke pain is called post-stroke pain syndrome. Causes and symptoms of cerebrovascular surgery experts, the first affiliated hospital of the PLA general hospital neurosurgery director of the expert professor said that the mechanism of post-stroke pain syndrome is still unclear, clinical observation found that most of the patients regardless of the normal or abnormal temperature or stimulation, will show an overreaction or slow response, so some scholars believe that this disease may be caused by the medial thalamus system of the conduction pathway in the inhibitory function of the fibers are damaged, the inhibitory effect on the stimulus response weakened caused by the stimulus. It has been suggested that this disease may be caused by damage to the inhibitory fibers in the medial thalamus conduction pathway and a weakening of the inhibitory effect on stimulus responses. It has been found that the key factor causing post-stroke pain syndrome is not the extent of the stroke, but the location of the stroke, and the common sites that can cause post-stroke pain syndrome include: dorsolateral medulla oblongata, thalamus, posterior limb of the internal capsule, and the cortex or subcortex of the postcentral gyrus, of which the dorsolateral medulla oblongata and the thalamus are the most common. 1995, Andersen et al. followed 191 stroke patients. In 1995, Andersen et al. followed 191 stroke patients, and the prevalence of pain syndromes was 4.8%, 6.5%, and 8.4% at 1, 6, and 12 months after onset, respectively, with the medulla oblongata and thalamus as the main sites of stroke.In 1999, MacGowan et al. reported that the prevalence of pain syndromes was as high as 25% in patients with medullary dorsolateral cerebral infarcts. The pain syndrome usually occurs in patients with less severe ischemic strokes and is more prevalent in the younger age groups, and is more common in men than in women. It does not usually occur immediately after a stroke, but mostly occurs 3-6 months after the stroke. Experts say that the clinical manifestations of post-stroke pain syndrome are complex and varied, and the range of involvement is generally large, often involving half of the body or half of the head and face. If the stroke is in the thalamus or the posterior limb of the internal capsule, pain may be present throughout the entire half of the body on the side opposite the stroke, including the head, face, and trunk. If the stroke site is in the dorsolateral medulla oblongata, it may manifest as pain in the head, face, and contralateral trunk on the same side of the stroke. The nature of the post-stroke pain can be characterized as burning, cutting, chiseling, tearing, or squeezing, and these pains can occur alone or in combination. Burning pain is the most common, occurring in more than 60% of patients with post-stroke pain syndrome, sometimes in combination with 1-2 other types of pain. The pain is often diffuse, with precise localization, and the pain is often severe and intolerable. The majority of post-stroke pain persists and tends to worsen progressively with the duration of the disease. In addition, a variety of factors can cause paroxysmal pain exacerbation on the background of persistent post-stroke pain, for example, emotional changes, muscle contraction, limb movement, hot and cold stimuli, and even touch, wind, etc., are able to induce pain or aggravate pain. In addition to pain, post-stroke pain syndrome is almost always accompanied by other positive neurological signs and symptoms, the most common being sensory abnormalities such as hyperalgesia and hypoalgesia, while others may include paralysis of the limbs, ataxia, choking and coughing, hoarseness, diplopia, aphasia, and a positive pyramidal tract sign. Experts believe that post-stroke pain syndrome is not an independent disease, but a series of clinical symptoms triggered by a variety of factors, both pathological and psychosomatic. Post-stroke pain syndrome will cause heavy mental stress to patients, seriously affecting the quality of life of patients, and should cause great concern to society, especially doctors, and give active treatment according to different situations. Commonly used treatment methods Experts say that with the integration of traditional medicine and modern medicine and the intersection of multiple disciplines, the treatment of post-stroke pain is no longer limited to a certain therapy, but must take a comprehensive treatment approach. At present, the commonly used treatment methods include drug therapy, traditional Chinese medicine internal and external use, psychological support, rehabilitation, acupuncture and surgical means. Commonly used therapeutic drugs include tricyclic antidepressants, anticonvulsants and opioids. Tricyclic antidepressants are the first line of treatment for neuropathic pain. Studies have demonstrated that gabapentin and pregabalin among the anticonvulsants are effective and well tolerated for both central and peripheral neuropathic pain. Opioids are generally not used as first-line medications due to their severe withdrawal symptoms. Pregabalin is the only drug approved for central and peripheral neuropathic pain and can effectively relieve post-stroke neuropathic pain, as well as improve patient sleep quality. In recent years, motor cortex electrical stimulation has gradually begun to be used in the treatment of this type of pain and has achieved more satisfactory analgesic effects. Chinese medicine believes that the pain caused by post-stroke is mostly due to qi stagnation and blood stasis, stasis and blood obstruction, and advocates that eliminating blood stasis and clearing up collaterals, moving qi and relieving pain should be the mainstay of the treatment, and that through the internal plus external use of traditional Chinese medicines, tendon relaxation and collaterals activation can be carried out, and blood stasis and relieving pain can be resolved. For localized pain such as shoulder-hand syndrome, massage and acupuncture can be performed. For pain caused by psychological and mental factors, it can be treated through psychological counseling and psychological suggestion. 8 kinds of people rush to screen for stroke “Stroke” commonly known as stroke, in recent years the incidence of increasing, increasingly younger, the culprit is an unhealthy lifestyle, it is worth everyone’s vigilance. How to catch the lurking killer of stroke as early as possible? High-risk groups must do timely screening. In the past, there were 8 risk factors for stroke, but nowadays it is refined to “4+12”, a total of 16 risk factors. If you have 1 of these 8 risk factors, you should be screened: blood pressure at or above 140/90 mm Hg; atrial fibrillation or valvular heart disease; smoking; dyslipidemia; diabetes mellitus; little physical activity; being significantly overweight and a family history of stroke. Of the newly refined 4 major risk factors and 12 general risk factors, you should be screened for stroke if you meet two of the major risk factors, or if you meet one major risk and two or more general risk factors, or if you have had a previous stroke/transient ischemic attack.4 major risk factors: hypertension, hyperlipidemia, diabetes mellitus, and being older than 50 years.12 general risk factors: Atrial fibrillation, heart disease; respiratory sleep apnea; family history of stroke; smoking; heavy alcohol consumption; physical inactivity; excess dietary fats and oils; obesity; being male; frequent bleeding gums, loose teeth, and loss of teeth; ischemic eye disease and sudden deafness. The correct procedure for screening should be to have a risk factor assessment at the stroke clinic, followed by routine blood tests, blood biochemistry, homocysteine, coagulation, blood sedimentation, glycated hemoglobin, and cerebrovascular ultrasound, electrocardiogram, and other tests, if necessary. After the examination, cerebrovascular CT, MRI and cerebral angiography will be done if necessary. After combining the two screening tests, patients who are diagnosed as high-risk group for stroke and have higher risk factors should receive drug interventions and life guidance, while patients with lower risk factors can only make adjustments to their diet and exercise. Patients diagnosed as high risk for stroke should go for regular checkups. Once every three months for ordinary patients and once every half a month or one month for patients receiving drug intervention, and the doctor will adjust the medication according to the side effects of the drugs.