Mycoplasma pneumoniae antibodies are divided into two types: IgM and IgG, the former positive indicates recent infection, while the latter positive indicates infection and the presence of antibodies in the body, and IgG is also of diagnostic value if it has increased fourfold or more in two recent tests. Mycoplasma pneumoniae pneumonia is a common disease in children and young adults. Most adults already have antibodies in their serum and therefore rarely develop the disease. The common clinical symptoms are in the form of bronchitis, pneumonia, and otitis media, and about 1/3 of patients are asymptomatic. The initial onset of the disease may include fever, sore throat, headache, malaise, nausea, vomiting, and in 2-3 days there may be obvious respiratory symptoms such as coughing and sputum with blood in the sputum. Some fevers can last for 2-3 weeks. Treatment: Early use of appropriate antibacterial drugs can reduce symptoms and shorten the course of treatment. Most patients can heal spontaneously without treatment. Macrolide antibiotics such as erythromycin, roxithromycin, and especially azithromycin are better than erythromycin for treatment. It is the drug of choice for Mycoplasma pneumoniae pneumonia. The course of treatment is about 2 weeks. In the later stage, if there will be a combination of bacterial infection, the drug can be selected according to the condition and bacterial culture results. Generally, antibody positivity can last for 3-6 months before it turns negative naturally. Therefore, treatment should not be selected for antibody positivity.