High cardiac enzymes indicate myocardial cell damage and necrosis, which is common in cases such as acute myocardial infarction, and should be taken seriously and seen by a hospital as soon as possible to avoid critical situations. Cardiac enzymes are present in cardiac muscle cells and can be detected in the blood after myocardial cell necrosis, and are commonly used as a marker of myocardial necrosis in clinical practice. High myocardial enzymes can be seen in acute myocardial infarction, where myocardial enzymes can be elevated several times or even hundreds of times, or in acute myocarditis, severe heart failure, or acute infection of other organs such as acute pancreatitis, where an elevated myocardial enzyme would indicate myocardial damage. The severity of myocardial enzyme elevation is directly related to the extent of myocardial damage, so when myocardial enzyme is severely elevated, it means that myocardial cells are severely damaged, leading to heart enlargement, heart failure, severe arrhythmias, and sudden death, which can endanger patients’ lives. In summary, elevated cardiac enzymes are an important indicator for the diagnosis of acute myocardial infarction and must be given high priority. However, elevated myocardial enzymes do not necessarily mean myocardial infarction, and need to be differentiated from other diseases that cause elevated myocardial enzymes. High cardiac enzymes can also be due to other cardiac causes such as myocarditis, and may also have other non-cardiac causes.