Recently, the Second Department of Neurosurgery of our hospital successfully performed a brain pacemaker implantation surgery for a patient with Parkinson’s disease who had been suffering from the disease for 8 years. The success of this surgery signifies that the level of Parkinson’s disease surgery and diagnosis and treatment in the Department of Neurosurgery of our hospital has risen to a new height. After the surgery, the patient could walk, turn around, turn over, dress and eat independently, and the limb stiffness disappeared. The neurosurgeon brought precise neuromodulation surgery to the patient, and the patient is about to return to a good family and happy life. Patient Liu XX, male, 62 years old, Jiaxiang County, was admitted to the Department of Neurosurgery of our hospital on October 10th due to stiffness and tremor of the limbs for 8 years. The patient started to walk unsteadily 8 years ago and had difficulty in starting and turning around. When walking, the body leaned forward and the swing of both upper limbs was reduced. This was accompanied by slow movements of both upper limbs and unsteadiness in holding objects. Then slowly appeared slurred speech, slow speech, low voice, sometimes salivation at the corners of the mouth. She could still brush her teeth and wash her face alone. She went to several hospitals in China and was diagnosed with Parkinson’s disease. After taking “Dobasic hydrazide tablets” and other medications, her symptoms improved and she kept adjusting her medication, and later added “Benzhexol hydrochloride tablets and piribedil extended-release tablets” to her treatment. One year ago, the patient’s condition was aggravated, and he had difficulty in walking and slow reaction, which was more obvious at night, and he had poor sleep at night and nightmares, and sometimes he could not control himself in urination. Half a year ago, the patient’s symptoms further deteriorated, drugs can not control the development of the disease, the patient has been unable to turn over on their own, dress and eat, limbs and trunk muscle tone further enhancement, life has been completely unable to take care of themselves, the need for family members to accompany twenty-four hours a day, the patient’s fear has further increased, very painful. The instinctive desire for a better life prompted the patient and his family to look for a cure. After consulting with a number of hospitals in China, making inquiries among his friends, and checking the Internet, the patient finally decided to come to our neurosurgery department for a brain pacemaker surgery to solve his gradually deteriorating condition. After the patient was admitted to the hospital, the director of the neurosurgery department of the hospital attached great importance to the patient’s condition and organized experts from the hospital’s multidisciplinary Parkinson’s Disease Diagnostic and Treatment Center to discuss and consult the patient’s condition again. The experts discussed that the patient’s condition is serious and his life is completely unable to take care of himself, which seriously affects the patient’s quality of life and also brings a heavy burden to his family. Cranial MRI examination found that the patient was combined with severe cerebral atrophy and cerebral infarction, which made the surgery difficult and risky, but the patient’s health condition would further deteriorate and even jeopardize the patient’s life if the patient did not undergo surgical intervention in a timely manner. As a result, the Parkinson’s surgery team headed by Dr. developed a scientific and standardized individualized surgical diagnosis and treatment plan for the patient and communicated and coordinated with the imaging department, operating room, neurophysiology experts and engineers in advance to make full preparations before the surgery. At the same time, we reported to the leadership of the hospital and the medical department, and the president instructed the Department of Neurosurgery to keep pace with the international and domestic new technologies, and make every effort to carry out this new technology, which represents the international first-class level, to relieve the patient’s pain. The operation was carried out on October 13 as scheduled. Firstly, a stereotactic head frame was installed on the patient’s head, and then the patient went to the CT room to have a 64-row CT thin-layer scanning of the cranium and brain, and then the surgical planning system fused with the cranial and cerebral MRI to calculate the coordinates of surgical target points. After entering the operating room, a small opening of about 5 centimeters in length was made on each side of the forehead of the patient’s head, and the stereotactic apparatus was adjusted according to the calculated coordinates of the target point, and the electrode of deep brain electrical stimulation was slowly implanted into the target point of the thalamus nucleus. Neuroelectrophysiologic recordings of EEG activity confirmed the accuracy of the target point. In order to verify the effect of the surgery, we talked with the patient during the surgery and found that the patient’s speech function improved significantly, his speech became fluent and clear, his voice became clear and loud from a weak voice, his eyesight became clear, and the patient’s stiff limbs loosened up significantly, and he could independently complete the double-legged stomping-like movement on the surgical bed, which was close to the normal limb function. The patient realized that the effect of the surgery was so immediate that it was hard to suppress his excitement, and frequently said that the surgery was amazing, which made him feel the taste of a healthy and normal life again. After the electrode implantation was completed, the stereotactic head frame was removed from the patient’s head, and under general anesthesia, the neurostimulator was implanted subcutaneously into the patient’s left chest and connected to the head brain stimulation electrode. The whole operation took 268 minutes and was successfully completed. On the third day after the operation, the patient could walk, turn around, turn over, dress, eat and other movements by himself, and the limb stiffness disappeared. The patient’s lover said: “There are 6, 7 years, the patient’s condition gradually aggravated, looking at his pain, the family heart is also difficult, I have not slept a whole sleep at night, the whole night guarding him, and now see him back to health, our whole family is very happy.” The patient’s family even claimed that the surgery was effective and that it had brought happiness to the whole family. The patient was discharged from the hospital on October 24th. One month after the surgery, after the brain pacemaker is turned on, the experts will perform precise neuromodulation for the patient, and the patient will usher in a beautiful family life. The treatments for Parkinson’s disease include medication, surgery, exercise rehabilitation, psychotherapy, etc. Compared with other surgical treatments, the most mature and advantageous one is “Deep Brain Stimulator Implantation”, or DBS for short, also known as Brain Pacemaker. In order to provide patients with individualized and optimized comprehensive treatment plans, our hospital has set up a Parkinson’s disease neuromodulation expert group composed of neurology, neurosurgery, imaging, and psychology, and established the Parkinson’s Disease Diagnosis and Treatment Center of the Affiliated Hospital of Jining Medical College, which realizes the integration of Parkinson’s disease diagnosis, screening, evaluation, medication, surgical treatment, and postoperative long-term management, and the “multidisciplinary synthesis, multi-disciplinary management” and “multi-disciplinary treatment, multi-disciplinary management, multi-disciplinary management, and post-operative management” of Parkinson’s disease. It aims to help patients with Parkinson’s disease, dystonia, idiopathic tremor and Tourette’s disease in the whole process of management, giving them one-stop management from the early drug treatment, the late pacemaker surgery, as well as postoperative program control, rehabilitation, psychological guidance and intervention, etc., giving full play to the therapeutic advantages of the multidisciplinary team, and providing patients with the most effective and efficient treatment for Parkinson’s disease. The treatment advantages of the multidisciplinary team are utilized to maximize the treatment effect for patients.