Antibiotics are used to treat bacterial infections. The pathogen of pneumonia in novel coronavirus infection belongs to the virus, and taking antibiotics not only has no preventive and therapeutic effect, but may lead to adverse drug reactions and even destroy the normal intestinal flora, so it is not recommended to apply antibiotics to pneumonia in novel coronavirus infection. Special attention should be paid to pregnant and lactating women, and those with severe renal insufficiency, who must use such drugs with caution. In the case of novel coronavirus, the treatment in the clinic is still mainly symptomatic.