The pancreas is the largest endocrine organ in the human body, mainly secreting hormones such as insulin and glucagon to control blood sugar and gallbladder contraction hormone and gastrin to regulate digestion; it is also an important exocrine organ, mainly secreting pancreatic juice containing pancreatic enzymes to digest food. The pancreas is located in the deepest part of the abdominal cavity, so once a tumor grows in the pancreas, the symptoms are not obvious and are not easily detected in the early stage. When symptoms such as back pain and weight loss appear, most patients are already in advanced stage. Therefore, the surgical resection rate is very low, even less than 20% at one time. Even after resection, it is easy to recur and metastasize, so it is one of the tumors with the worst treatment effect, so it is often called the “king of cancers” and most people are afraid of talking about pancreas. However, with the improvement of people’s living standard, the popularization of health awareness and the advancement of medical technology, many very early pancreatic tumors can be detected. Ultrasound is the preferred method of examination, and experienced doctors can detect pancreatic cysts of about 5 mm, while CT, MRI, selective angiography and other imaging tests can detect tumors of 1 cm or less. There is also endoscopic ultrasound, i.e. ultrasound examination of the pancreas through gastroscopy, which can not only detect subtle lesions, but also perform ultrasound-guided puncture biopsy of the mass for qualitative diagnosis. The vast majority of tumors found in this case can be resected, and the prognosis is greatly improved after resection of tumors at such an early stage. In addition to earlier detection and higher resection rate, more importantly, pancreatic tumor resection has also become more precise. In the past, even benign tumors in the head of the pancreas must be removed by pancreatic head duodenectomy, which requires removal of the gallbladder, common bile duct, duodenum, distal stomach, head of the pancreas, and proximal part of the small intestine, which is the largest operation in traditional abdominal surgery. For tumors in the middle part of the pancreas, in the past, a more invasive resection of the tail of the pancreas combined with splenectomy was required, but now it is possible to perform resection of only the middle part of the tumor. All benign endocrine tumors of the pancreas can be locally resected. In this way, the lesion is removed while the pancreatic tissue is preserved, and the tumor is removed with minimal cost. This method, medically known as local resection of pancreatic tumors with preservation of organ function, has only been gaining attention in the last decade. It is also a newer surgical concept and technique that has only been gradually emphasized in the last decade. Another great progress is the minimally invasive surgical technique. Laparoscopic surgical techniques are now more maturely applied in the field of hepatobiliary and pancreatic surgery. More than 95% of gallbladder resections can be done laparoscopically. Minimally invasive laparoscopic surgery of the pancreas can also be done for local excision of tumors, caudal resection of the pancreatic body with preservation of the spleen, and larger pancreaticoduodenectomy. The incision is small, painless, and recovery is quick, and you can get out of bed on the 2nd day and be discharged from the hospital in 3 to 5 days after surgery. The application of surgical robots has also led to a new era of minimally invasive pancreatic surgery. Therefore, the discovery of pancreatic tumors, at least some benign tumors, need not be overly nervous, and there is no need to “talk about pancreas”.