If you have a fever at night, you can choose physical cooling if it is not convenient to see a doctor, such as making a pillow with an ice pack to put on your neck, or you can choose to put a cool towel on your forehead, in addition to taking some alternate fever-reducing medications, such as acetaminophen tablets and ibuprofen capsules. If the fever is accompanied by some symptoms of cough, sore throat and runny nose, it may be an upper respiratory tract infection, and you can take oral medication for cold and fever. Many conventional cold medicines have fever-reducing ingredients inside, such as cold and flu granules, aminogalactam capsules, compound aminogalactam tablets, wind and cold granules, etc. For unexplained fever, body temperature over 38.5℃, if the situation is urgent, you can apply acetaminophen tablets or ibuprofen extended-release capsules to reduce fever, in addition to drinking more water to replenish the body’s water loss due to high fever. If the home is close to the hospital, it is best to go to the hospital for blood tests, such as routine blood tests, C-reactive protein, and mycoplasma pneumoniae chlamydia tests, to identify the cause of the disease and then treat it symptomatically. If the patient’s condition is serious, such as the appearance of unconsciousness, breathing difficulties and other manifestations, he or she should promptly go to the hospital to see a doctor for treatment. Therefore, when fever occurs at night, if the patient is generally well and the body temperature is not very high, the patient can be cooled down with physical or medication first, and then decide the next treatment according to the severity of the patient’s condition and the effect of heat treatment, and go to the hospital if necessary; for infants and young children with persistent high fever patients should prevent the occurrence of high fever convulsions.