There are 3 routes of bacterial infection of the orbit: 1. Direct infection of the orbit: superficial trauma to the skin including insect bites and trauma to the eyebrows may lead to preorbital septum. Trauma to the orbit causes cellulitis with or without the presence of foreign bodies. Orbital fractures, however, cannot be diagnosed to result in cellulitis. 2. Extension of nearby tissues: Inflammation of the sinuses is the most frequent cause of orbital cellulitis, and a portion of the orbital septum anterior cellulitis is also responsible for it. It may enter through direct diffusion, i.e., the natural crevices of the medial wall of the orbit, or through thrombophlebitis or the venous valves of the orbit. In addition, the septal sinus is a more common cause. Dacryocystitis and skin infections may be more common causes of anterior septal cellulitis. Also odontogenic as well as otitis media have been reported. Dacryoadenitis and endophthalmitis rarely infect orbital cellulitis. Ocular surgery such as strabismus, glaucoma, and retinal detachment have also been reported to cause orbital cellulitis. Trauma-induced oral mucosal infections may complicate anterior septal cellulitis. 3. Hematogenous: Rarely, inflammation of the orbit is due to bloodstream infection. Anterior cellulitis of the orbital septum caused by upper respiratory tract infection in children.