Vitiligo is a common acquired disease of limited or generalized skin pigmentation loss. It is caused by loss of melanocyte function in the skin, but the mechanism is not clear. It can occur on all parts of the body, commonly on the back of the fingers, wrists, forearms, face, neck, and around the genitalia. It can also occur in the vulva of women, mostly in young women.
A, drug treatment 1, immunomodulators levamisole oral, lyophilized BCG vaccine (BCG) intramuscular injection, oral bovine placenta, etc.; 2, large doses of vitamins such as vitamin B, vitamin C, vitamin P long-term administration; 3, psoralen and its derivatives such as methoxsalen oral exposure to ultraviolet light; 4, useful copper-containing drugs such as 0.5% copper sulfate solution oral treatment; 5, corticosteroids various Corticosteroids such as beclomethasone propionate ointment, halometasone cream, deinflammatory pine urea ointment and other local sealing treatment; 6, skin stimulants local rubbing to make the skin inflammatory reaction, to promote pigmentation, commonly used 30% tincture of bone marrow, nitrogen mustard alcohol, phenol (pure carbolic acid), 25% to 50% trichloroacetic acid, tincture of zebrano, etc. This method is only applicable to small lesions, and large blisters can appear at the lesions after coating.
Second, surgical treatment Patients with stable lesions without progression can perform autologous epidermal transplantation.
The treatment is suitable for those with large lesions, more than half of the body surface area, and can be applied externally with 3%-20% hydroquinone monoanisole cream.
Physical therapy Narrow-wave UV, long-wave UV or 308nm excimer laser treatment.