Bone metastasis is one of the manifestations of advanced malignant tumors, mainly manifested as local pain, especially heavy at night, peripheral bone metastasis bone destruction, mainly pain, if the spinal metastasis in addition to low back pain, often lead to compression of the spinal cord, resulting in paraplegia, the consequences of a serious, sharp decline in the quality of life, so once the spinal metastasis, it is necessary to treat the spinal metastasis as soon as possible, the prevention of paraplegia is the key. It is common to see cases of paraplegia due to lumbar pain in patients with tumors. The treatment of bone metastasis is more complicated. If a single vertebra is destroyed, the patient is in good health, and the primary tumor is well controlled, it can be treated by surgery, but most of the patients don’t have the chance to have surgery, so they need palliative radiotherapy. Radiotherapy can relieve pain with high efficiency, up to 80%, prevent further bone destruction, re-calcify the destroyed bones, reduce the soft tissue mass, and prevent paraplegia. Niu Po, Radiotherapy Department, Henan Provincial People’s Hospital The treatment of multiple bone metastases should be different from person to person. For multiple metastases in vertebrae, radiotherapy should be given as the main treatment to prevent paraplegia; if the lesions are widely distributed, radiotherapy can be given in sections, which can be combined with pain-relieving medicines and phosphate medicines.