The development of gynecologic inflammatory diseases is clinically considered to be closely related to the development of infectious pathogenic microorganisms, so the current treatment of gynecologic inflammatory diseases is mainly aimed at the treatment of specific pathogenic microorganisms. Gynecological inflammation can be divided into two categories according to the pathogenic microorganisms. The first one is common gynecological inflammation, such as bacterial vaginosis, mycotic vaginitis, senile vaginitis, etc. These vaginal inflammations are usually caused by common pathogenic microorganisms and can be treated with topical drugs, most of which can be cured in one course. The second type of vaginal inflammatory disease is sexually transmitted vaginitis, which is contagious and spread through sexual intercourse. The clinical treatment of these gynecological inflammatory diseases mostly involves simultaneous treatment of the patient and the sexual partner. The choice of medication requires different symptomatic treatments depending on the type of inflammation. Regardless of the type of gynecological inflammation, laboratory tests of secretions are required after a course of treatment. If the treatment is not effective, additional medication will be required. In summary, most gynecological inflammatory diseases can be treated with topical vaginal medications.