Pre-diabetes is possible to relapse after five years of normalization, mainly related to ageing, lifestyle, other diseases and genetic factors. 1. Age: too old, blood sugar regulation function is relatively poor, pre-diabetes may recur, or even develop into diabetes. 2. Lifestyle: Whether or not pre-diabetic patients relapse is closely related to their dietary habits, the control and adjustment of dietary structure plays an important role in maintaining blood glucose, it is recommended to adhere to a low glycemic diet and control weight gain. In addition, exercise habits and sleep habits are also related to relapse. 3. Other diseases: If you suffer from hypertension, hyperlipidemia, gout, etc., the risk of diabetes recurrence is higher. 4. Genetic factors: whether prediabetes will recur is also closely related to genetic factors, the family has diabetes patients, the possibility of recurrence is also relatively high. After the pre-diabetes patients are normal, they should have regular checkups to monitor the changes in blood glucose, and treat them as early as possible once they relapse.