Parkinson’s disease mainly affects people’s limb movement function, leading to patients to take care of their own life becomes difficult, once diagnosed, can not be separated from the drug treatment, there are many therapeutic drugs, the role of different, early scientific use of medication, basically can be very good to improve the symptoms, to be able to take care of their own life. Parkinson’s disease patients can take medication to improve symptoms, but can not stop and change the development of the disease, in order to live a better life, patients will think of brain pacemaker surgery. Is any patient a good candidate for surgery? Should surgery be done earlier or later? Let’s take a look at the treatment experience of this Parkinson’s disease patient. Early Parkinson’s disease first consider drug treatment, general drug treatment has a honeymoon period of 3 to 5 years, indicating that the medication has a very good efficacy, after the honeymoon period, the effect of the drug will gradually decline, can not be very good to improve the symptoms, to such an extent that many patients will want to increase the dosage of the drug on the line, which is not desirable, because the drugs have side effects, increase the dosage of the drug may make the motor complications come faster, such as Switch phenomenon, anisotropy, etc. This is not advisable because all medications have side effects. Drug treatment needs to follow the “individualized”, Parkinson’s disease is a chronic progressive disease, need to consider for the long term, it is recommended that patients have the disease to find a doctor, under the guidance of a professional doctor to use drugs, scientific treatment. Early drug effect is good, first drug treatment, do not consider surgical treatment for the time being, when the scientific use of medication, drug effect declines, the emergence of motor complications, this time to consider surgical treatment to improve the symptoms, can not be delayed to a very late stage, because the operation must take into account the patient’s age, physical condition, assessment of the risk and so on. Therefore, surgery should not be done early or late, but at the right time to improve symptoms and quality of life. Brain pacemaker surgical treatment has strict control, not all Parkinson’s disease patients can do, before the operation, the patient is hospitalized to check the physical condition in detail, routine blood sampling, electrocardiogram, brain MRI’s, psychosomatic scale, etc., and the Medopa impact test to observe the rate of improvement, all the results of the examination come out, the department discusses, and comprehensively evaluates the patient’s ability to do the surgery, and if there is no contraindication to the surgery, then the surgery can be arranged for a period of time, and the surgery can be performed. Surgical treatment was performed. After the implantation of the stimulation electrodes and pulse generator of the pacemaker, it cannot be turned on immediately, and it takes about one month for the patient to recover and come back to the hospital to turn on the pacemaker. The pulse generator of the pacemaker has a service life, as long as the pulse generator has power, the patient’s symptoms will be maintained in a stable state, even if the disease progresses over time, it is only necessary to come to the hospital for the programmed control, adjust the parameter values, and continue to achieve a new balance, if the pulse generator power is exhausted, it is necessary to be hospitalized to replace the pulse generator with a new one.