A fracture is a disorder in which the continuity of bone is interrupted due to trauma or pathological factors. We are all familiar with fractures because they are very common around us. Some people may fall and fracture their bones with a little focus. After treating the fracture, doctors often also instruct patients not to smoke or drink in the near future. Why is this? Let’s talk about the effects of smoking on fracture healing. There are no experimental reports on people at home or abroad, but we can get some preliminary conclusions on some animal experiments. We all know that tobacco contains a chemical called nicotine, which has been shown to cause delayed healing of fractures. On the one hand, nicotine causes inflammation of the respiratory tract, hinders gas exchange between the body and the environment and decreases oxygen saturation in the blood, on the other hand nicotine also causes spasm of the tiny blood vessels and prevents oxygen exchange between them and the tissue cells. Under hypoxic conditions tissues cannot produce enough type I collagen, which is one of the main components indispensable for new bone production. In addition, tobacco-induced physiological changes are also manifested in the bone marrow. Smoking significantly reduces the oxygen-carrying capacity of red blood cells, so the bone marrow has to produce more red blood cells to maintain oxygen levels in the body. Many types of blood abnormalities are associated with smoking, and high levels of carbon monoxide in smokers bind to hemoglobin in red blood cells, reducing the oxygen-carrying capacity of red blood cells and reducing the amount of oxygen entering the tissues, also affecting fracture healing. Theoretically, smokers have increased erythrocyte volume in venous blood, increased fibrin levels, increased blood viscosity, and more pronounced erythrocyte agglutination, thus slowing blood flow to the fracture area in smokers and severely affecting the fracture healing process. Therefore, during the healing phase of the fracture, those who have a smoking addiction should pay extra attention to it. Many people think that drinking alcohol after a fracture can invigorate the blood and is good for fracture healing, but this is not true. Current medical knowledge tells us that various biochemical factors must be involved in fracture healing, including cytokines, proteases, and angiogenic factors. The formation of blood vessels and blood flow determines how well the fracture heals. Once alcohol is consumed excessively, there is an excess of ethanol in the body, which leads to disorders of fat metabolism and its toxic effects increase the production of free radicals, resulting in a decrease in the activity of superoxide dismutase (SOD), one of the main scavengers of free radicals, which has a strong role in triggering lipid peroxidation, leading to damage to the endothelium of blood vessels, fibrous degeneration and atherosclerosis of small arteries, resulting in inadequate blood supply to the fracture site, while fat in the peripheral circulation At the same time, the increase of fatty substances in the peripheral circulation and their aggregation into fat globules slow down the blood flow and make it easy to embolize small arteries, and due to the compression of blood sinus by proliferating fat cells, the pressure in the bone trabeculae increases and the microcirculation stagnates, which makes the formation of bone at the fracture encounter obstacles and affects the fracture healing. As for some medicinal wines that have the effect of activating blood circulation and removing blood stasis in Chinese medicine, they should be used under the guidance of a doctor as much as possible. Although the fracture is not a major disease, if it keeps growing badly, it will bring a lot of trouble and cause unnecessary pain and burden to the patient. Therefore, in addition to receiving regular treatment, one’s bad habits should also be corrected in time for an early recovery.