Diagnosis and treatment of tumors in the elderly

It is estimated that 20% of the U.S. population will be over 65 years of age by 2030. More than 50% of all new tumors in the United States occur in people aged ≥65 years. The incidence of tumors in China is also increasing year by year, the rising trend in rural areas is greater than urban areas, and women are greater than men, and tumor patients are expected to increase year by year. Tumors are the leading cause of death among people aged 60-79. In addition, although some tumors (e.g., breast or lung cancer) may be pain-relieving, the prognosis for certain types of tumors becomes worse with age (e.g., acute granulocytic leukemia, large cell non-Hodgkin’s lymphoma, malignant astrocytoma, osteogenic sarcoma). The increasing incidence and prevalence of tumors in the elderly and the rising life expectancy mean that tumors have gradually become an increasingly common disease among the elderly. I. Characteristics of tumors in the elderly In addition to the characteristics of general tumors, tumors in the elderly have their own special characteristics: 1. clinical symptoms are mild and easy to be ignored; 2. relatively slow development and low metastasis rate; 3. more deaths due to complications; 4. more asymptomatic latent tumors; 5. more primary cancers; according to statistics, multiple malignant tumors account for about 10% of tumors in the elderly; the older the age, the higher the proportion of multiple tumors. Because of the above-mentioned special characteristics of tumors in the elderly, they should be highly regarded by the elderly. Because of the decline of their own organ functions, the emergence of many chronic diseases, family economic conditions and many social factors, the treatment of tumors in the elderly is not possible like that of young patients and needs individualized treatment. First, oncologic treatment of the elderly requires a comprehensive assessment to screen which patients may benefit from comprehensive treatment. Assessing whether the expected outcomes after treatment of people with reduced life expectancy and reduced treatment tolerance are better than the risks they take in treatment is key in dealing with elderly oncology patients. Second, choose the appropriate treatment. Age is not a primary consideration for surgical risk. However, caution should be used when combining radiotherapy; adjust the dose of chemotherapy if necessary. Chemotherapy can lead to a range of problems (e.g., neurotoxicity, cardiotoxicity, mucositis), and adequate precautions need to be taken. Focus on molecular targeted therapy. The existing research results have shown that molecular targeted therapy for tumors has a better safety and certain effectiveness. It is a better treatment choice for elderly malignant tumor patients because of its less damage and good tolerability. Thirdly, we should pay attention to nutritional support and the management of complications. Fourthly, we should pay special attention to TCM treatment. According to TCM, the elderly are the body with residual yin and yang, the five organs will be deficient and the yin and yang will be out of balance, so they are prone to various diseases. As the saying goes, “If you are weak as a wind candle, you are prone to all kinds of diseases”. Therefore, Chinese medicine treatment must pay attention to support and regulate the righteousness, and drive away the evil at the right time. However, we need to pay attention to the following points: pay attention to the combination of dialectical evidence and disease identification; pay attention to the quality of life conditioning, light tumor size; pay attention to Chinese medicine, do not abandon Western medicine; pay attention to tumor treatment, do not forget the management of complications. Fifth, do not forget psychological guidance. Through reasonable treatment, elderly tumor patients can live longer with tumor, improve their quality of life and enjoy their old age peacefully.