How is cachexia caused?

  The symptoms include anorexia, chronic nausea, constipation, weakness of limbs, depression, change of physical appearance, etc. On the one hand, these patients lose their appetite, and on the other hand, even supplementation is not always effective, but due to the progress of science and the understanding of the causative mechanism of cachexia, there are already drugs that can improve cachexia.  It is because the tumor changes the metabolism of the body through various ways, so that the body cannot absorb nutrients from outside, and the tumor takes nutrients from the body’s inherent fat and protein to build itself, so the body loses a lot of nutrients, especially essential amino acids and vitamins (formed by the decomposition of fat and protein). The oxidation process in the body is weakened, and the oxidation products are not fully utilized, resulting in a wasteful metabolism, insufficient calories, which causes loss of appetite, only a small amount of food or no food at all, extreme emaciation, skin and bones, only a skeleton, anemia, weakness, completely bedridden, unable to take care of themselves, extreme pain, general exhaustion and other syndromes.  The physiological state of cachexia is very peculiar, different from the general starvation state, in the general starvation state, the energy consumption in the body will be reduced, but the opposite of cachexia, in addition to not being able to eat, the body will continue to increase energy consumption, so try to eat but not fat, this often bother the family members of patients.