Positive fecal occult blood may be caused by peptic ulcer, anal fissure, gastric cancer and other diseases, different diseases, the use of different medications, you can follow the doctor’s instructions to use sodium bicarbonate, omeprazole, nitroglycerin ointment and other drugs, to treat the cause. 1. Peptic ulcer: it can cause positive fecal occult blood and recurrent rhythmic pain in the middle and upper abdomen, accompanied by regurgitation, belching (hiccups), nausea and other symptoms. Coffee, strong tea, spicy and stimulating food should be avoided, on this basis, the use of sodium bicarbonate, cimetidine, omeprazole and other drugs to inhibit gastric acid as prescribed by the doctor, and the use of bismuth potassium citrate, aluminum sulfate and other gastric mucosal protectants, if there is Helicobacter pylori infection, the need for the joint use of amoxicillin, clarithromycin, omeprazole, colloidal bismuth pectin and other drugs. 2. Anal fissure: it can also cause positive fecal occult blood, and when defecating, the anus has cut-like pain. It can follow the doctor’s instruction to use local lidocaine gel to reduce the pain, or use nitroglycerin ointment to relieve the symptoms, and if necessary, anal fissure resection and other surgical treatments are also needed. 3. Gastric cancer: irregular fever, abdominal pain, emaciation and other symptoms may appear, and routine fecal examination may find positive fecal occult blood. Surgery or radiotherapy should be performed according to medical advice. In addition, there are many other reasons that can cause positive fecal occult blood, so it is recommended that patients go to the hospital in time to find out the cause of the disease and actively cooperate with doctors for treatment.