In the later stages of cirrhosis, portal hypertension can lead to the formation of three collateral circulations, which refer to esophagogastric fundic varices, abdominal wall varices and hemorrhoidal varices. These three collateral circulations are actually formed mainly because of the obstruction of blood flow due to high portal pressure, which causes varices in the returning vessels and thus causes the corresponding manifestations. In the later stages of cirrhosis, these collateral circulations can cause more serious complications because of varices in the veins. For example, rupture of esophagogastric-fundus venous varices can cause major gastrointestinal bleeding or even death, and many patients with advanced cirrhosis die because of vomiting blood. And dilated hemorrhoidal veins can cause blood in the stool, which can also cause death. These patients can have their portal pressure reduced by TIPS surgery, thus reducing collateral circulation.