TumorMarker (TM) is a kind of substance that reflects the existence and growth of tumor, which is synthesized by the gene expression of tumor cells or produced abnormally by the body’s response to tumor during the process of malignant tumorigenesis and proliferation, and is of certain value for the auxiliary diagnosis, differential diagnosis, efficacy observation, recurrence monitoring and prognosis evaluation of tumor. Commonly used clinical tumor markers: Alpha-fetoprotein (AFP) —- Diagnosis, treatment monitoring and follow-up of primary hepatocellular carcinoma and embryonic cell tumors Alpha-fetoprotein heteroplasm (AFP-RL) —- Early diagnosis and differential diagnosis of hepatocellular carcinoma, follow-up monitoring of slow cirrhosis Carcinoembryonic antigen (CEA) —- Treatment monitoring of colorectal cancer and various adenocarcinomas Glycoantigen 125 (CA125) – -Ovarian cancer, pancreatic cancer adjuvant diagnosis, efficacy judgment and recurrence monitoring Glycoantigen 15-3 (CA15-3) —- Breast cancer therapeutic monitoring Glycoantigen 19-9 (CA19-9) —- Pancreatic cancer, liver cancer, biliary tract cancer, gastric cancer Adjuvant diagnosis, efficacy determination and recurrence monitoring Glycoantigen 724 (CA724) —- Gastric cancer, ovarian cancer therapeutic monitoring Prostate-specific antigen (PSA) Free prostate-specific antigen (FPSA) —- Screening, diagnosis, staging, efficacy observation and recurrence monitoring, prognosis determination of prostate cancer Neuron-specific enolase (NSE) —- Small cell lung cancer, neuroblastoma Human chorionic gonadotropin (HCG) —- germ cell tumor, choriocarcinoma diagnosis, treatment monitoring and follow-up Squamous cell carcinoma-associated antigen (SCC) —- cervical, pulmonary esophageal, anal, head and neck squamous cell carcinoma efficacy monitoring and prognosis judgment Tissue polypeptide antigen (TPA) —- lung, bladder cancer treatment monitoring Tissue polypeptide-specific antigen (TPS) (TPA) —- Breast Cancer Efficacy, Recurrence and Metastasis Monitoring, Diagnosis and Prognosis Cytokeratin 19 Fragment (CYFRA21-1) —- Lung and Bladder Cancer Adjuvant Diagnosis, Treatment Monitoring and Prognosis Estrogen Receptor (ER) —- Breast Cancer Hormone Therapy Prediction and Prognosis Progesterone Receptor (PR) —- Breast Cancer Hormone Therapy Prediction and Prognosis Thyroid globulin (TG) —- thyroid cancer treatment monitoring human calcitonin (hCT) —- medullary thyroid cancer adjuvant diagnosis and postoperative monitoring