When many Parkinson’s patients come to the outpatient clinic, they are trembling all over their body and their actions are completely unable to take care of themselves. When I asked the patients about their medication, many of them replied that although the medication had some effect (meaning that the patient’s symptoms could be relieved after taking the medication), we did not dare to take it, and we only took less than one tablet of Metoprolol (or Xionin) a day. When asked why they did not take more medication, the majority of patients answered, “I am afraid of the side effects of the medication. and “The internist doesn’t want us to take more medication!” and so on and so forth. After listening to these accounts, I feel that as a doctor specializing in Parkinson’s disease, it is very important for me to come forward and correct a huge misunderstanding that has existed for a long time about taking medication for Parkinson’s disease – “don’t look for the full effect, but take it slowly”. When I was a student (about twenty years ago), this approach to Parkinson’s disease medication existed, probably because there was no surgical treatment for Parkinson’s disease, so the early administration of large amounts of anti-Parkinson’s disease medication would result in significant “on/off” phenomena and anisotropy. The side effects of these drugs are difficult to resolve through the drugs themselves. However, with the advances in stereotactic technology and the advent of brain pacemakers, it has long been possible to surgically address these complications. If you, as a neurologist, are still telling Parkinson’s patients not to take more medication, and that some effect is enough, then you are undoubtedly planting a “hidden danger” for your patients. The consequence of this “hidden danger” is that if the patient’s disease course is too long, it will lead to deformation of the joints and spine, and the loss of motor function will lead to lifelong disability, and cannot be recovered. I have followed the treatment of Parkinson’s patients preoperative medication, the domestic patients preoperative about three tablets of Medoxomil (or resting), while in foreign countries is almost twice as much as ours. The huge difference in dosage of medication also creates a gap between the state of the patient before surgery. Therefore, rational Parkinson’s disease medication is so important for patients. If the patient develops a good medication habit before surgery, although the side effects of the medication (“on/off” phenomenon and anisocoria) may occur, the patient’s quality of life will be significantly improved before surgery, and the patient’s standard of living will be stepped up to a new level with the elimination of the medication’s side effects after the surgery.