Ultrasound diagnosis in China began in the late autumn of 1958 and was born in Shanghai. The Sixth People’s Hospital of Shanghai, with the help of Jiangnan Shipyard, succeeded in diagnosing tumor diseases with an industrial flaw detector (A ultrasound), and then established the Shanghai Ultrasonic Diagnosis Application Research Group, which jointly carried out technical research with many units and achieved fruitful results in a short period of time, publishing the first academic paper on ultrasonic diagnosis, holding the first ultrasonic diagnosis training class and publishing the first monograph on ultrasonic diagnosis, which rapidly spread ultrasonic The first academic paper on ultrasound diagnosis was published, the first training course on ultrasound diagnosis was held, and the first monograph on ultrasound diagnosis was published. At present, China is the country with the largest number of people benefiting from ultrasound diagnosis and the largest installed capacity in the world. Ultrasound technology has been developed to a new height, and its non-radiation, non-invasive, flexible and timely high-tech components have demonstrated its infinite charm and infinite broad prospects in the vast territory of the world’s largest developing countries. At present, ultrasound diagnosis is widely used in clinical practice, mainly in: 1. abdominal diseases. In the diagnosis of abdominal parenchymal organs, cavernous organs and retroperitoneal diseases. 2.Obstetrics and gynecology diseases. 3. Diagnosis of cardiac and peripheral macrovascular diseases. Ultrasound, with its non-invasive and color Doppler applications, enables the application of non-invasive examinations for the diagnosis of cardiovascular diseases. 4.Small organ diseases. Diagnosis of thyroid, breast, testis, epididymis and other diseases. 5, peripheral muscle nerve and other motor injury ultrasound diagnosis. 6.Intracavitary ultrasound. Transrectal, transvaginal, transesophageal ultrasound, in the field of ultrasound diagnosis continues to develop, the application is increasingly widespread. 7.Ultrasound endoscopy, intravascular ultrasound, intraoperative ultrasound. In addition, with the continuous development of biomedical engineering, ultrasound is not only applied in the field of diagnosis, its application in treatment is becoming more and more extensive. 1.Ultrasound intervention. The use of ultrasound guidance, targeted to complete a variety of treatments, can be puncture biopsy, tumor radiofrequency ablation, local drug injection and other clinical treatment, with no radiation, convenient, less traumatic and other advantages. 2.Ultrasound therapy. Using the physical effects of ultrasound such as thermal effect, cavitation effect and acoustic pore effect, ultrasound irradiation is directly applied to the lesion to achieve the biological effects of inducing apoptosis, necrosis and ablation of tumor cells and treating the disease. Moreover, ultrasound contrast agent can carry therapeutic drugs or therapeutic genes, which can achieve the advantages such as targeted release and strengthen the effect of ultrasound treatment. At present, high-energy focused ultrasound (HIFU) has been clinically applied and has achieved certain effects. 3.Anesthesia ultrasound. Using the advantage that ultrasound can show the nerve, using ultrasound guidance to complete nerve anesthesia, more accurate than the previous purely relying on anatomical positioning, more accurate anesthetic effect, and avoid unnecessary damage. With the continuous development of biomedical engineering, various new technologies will be continuously applied in ultrasound diagnosis and ultrasound treatment. The development direction of ultrasound in the future: 1. Constant updating of diagnostic technology. Based on the existing ultrasound diagnostic technology, three-dimensional ultrasound will be more perfect; magnetic resonance, CT and ultrasound image fusion technology will make the lesion more intuitive to display and more accurate lesion localization; more sensitive to tumor blood flow imaging; intracavitary ultrasound probe is more compact and flexible. 2. Interventional ultrasound will shine. Interventional ultrasound has achieved rich and positive results, and in the future, interventional ultrasound will shine with the application of new technologies. Volume navigation technology has been applied in the field of interventional ultrasound, which will expand the scope of application in the future, and the technology will be more mature; change the current treatment concept of single cold or single heat for ultrasound-guided tumor treatment, and adopt the new technology of alternating hot and cold treatment, which may increase the treatment effect; trauma will be further reduced, and recovery will be more rapid. 3.Ultrasound therapy is emerging. The direct use of ultrasound irradiation can treat the lesion, which is convenient and flexible for treatment. On the basis of the present, ultrasound therapy will further improve the conditions of ultrasound irradiation and develop new contrast agents, which can achieve ultrasound irradiation to promote local drug delivery and promote therapeutic gene transfection, etc., and be widely used in the treatment of various diseases.