Ms. Li was admitted to the neurosurgery department due to ventricular hemorrhage, and a tumor was found in the deep ventricle after MRI examination. After careful study of the medical history and imaging data, the neurosurgeons of our hospital recently successfully removed the patient’s deep brain tumor under the microscope with the help of neuroendoscopy and neuronavigation, and the patient had no significant neurological dysfunction after the operation. Dr. Zhang Jianping, the chief physician, introduced that the patient’s tumor was located in the deep left ventricle, and the traditional method of removing the tumor via cortical fistula would often cause the patient’s cognitive and language dysfunction and even limb paralysis. The posterior longitudinal fissure was used to access the tumor nearest to the medial side of the brain, avoiding the functional brain area, using neural navigation for precise positioning, and skillfully removing the tumor and intracerebroventricular blood accumulation under the surveillance of high-definition microscope and endoscope.