Arbutin is effective in removing spots, but the effect is often limited, and due to the different reasons for the formation of spots, arbutin has different effects on removing spots, usually due to congenital hereditary factors caused by spots, arbutin treatment effect may be smaller; if due to acquired factors caused by sun spots, chloasma, etc., arbutin has a certain effect of spot reduction, but need to be paired with other treatment methods. The principle of arbutin is that arbutin has a certain inhibitory effect on tyrosinase in human body, tyrosinase is an important enzyme in the process of melanin production, so arbutin can play a role in inhibiting melanin production in the organism, and it has a certain lightening effect on the spots caused by ultraviolet ray irradiation, endocrine abnormality and other increases in melanin production, but it is usually difficult to do a complete elimination. It is recommended that candidates in the use of arbutin at the same time, with laser, drugs and other treatments, and also need to pay attention to improve the skin caused by the triggers of spots, such as sunscreen, regulate the endocrine and so on, in order to play a better light spot effect; and for non-melanin deposition caused by the spot, arbutin’s role tends to be relatively small. In addition, it is recommended to use arbutin in moderation under the guidance of a doctor, so as not to use too much to destroy the melanin cells in the body, causing skin discoloration, skin inflammation and so on. Some people may be allergic to arbutin, if the use of arbutin after the skin redness, rash, itching, swelling and pain and other uncomfortable symptoms, it is recommended to stop using it immediately, if necessary, can be under the guidance of a doctor to carry out anti-allergy treatment.