Ectopic pregnancy is a condition in which a fertilized egg is affected by certain factors and takes up residence outside the uterine cavity. The timing of abdominal pain varies depending on the location of the ectopic pregnancy and the size of the gestational sac. In the early stages of ectopic pregnancy, there is usually no significant pain. As the gestational sac of ectopic pregnancy gradually increases in size, it will pull the pericardium of the pregnancy site and cause abdominal pain, and if the pericardium ruptures, it may also cause bleeding and the patient may experience vaginal bleeding and lower abdominal pain. In addition, the timing of abdominal pain in ectopic pregnancy is also related to its location. If the ectopic pregnancy occurs in the isthmus of the fallopian tube, it is likely to rupture around 6 weeks of gestation and cause abdominal pain; if it is in the jugular region of the fallopian tube, rupture is likely to occur at 8-10 weeks of gestation, followed by abdominal pain; while rupture of ectopic pregnancy in the interstitial region is the latest, usually occurring at 12-16 weeks of gestation, followed by abdominal pain. Once the patient is diagnosed with ectopic pregnancy, it is recommended to actively cooperate with the treatment and choose medication or surgery depending on the size of the ectopic pregnancy mass, the level of blood hCG and the presence of active bleeding in the pelvis.