Long-term use of contraceptives or glucocorticoids may induce heart disease, such as compound norethindrone tablets, dexamethasone, as well as potassium chloride, sertraline, etc. In addition, stress and smoking are also prone to induce heart disease. Estrogen contained in contraceptive pills can easily cause water and sodium retention, which will increase the burden on the patient’s heart, and may induce heart disease if long-term use of contraceptive pills such as compound norethindrone tablets and compound ethinyl estradiol tablets. In addition, taking glucocorticosteroids can also cause water and sodium retention, which will increase the load on the heart. If patients take glucocorticosteroids such as dexamethasone and hydrocortisone for a long period of time, heart disease may be induced. In addition, long-term use of potassium chloride, potassium citrate and other potassium agents, as well as sertraline, fluvoxamine and other antidepressants may also induce heart disease. In addition to this, chronic stress, smoking and alcohol abuse, a preference for diets high in salt, fat and sugar, or the presence of chronic diseases such as high blood cholesterol and high blood pressure may also induce heart disease. It is recommended that patients need to use medication under the guidance of a doctor, not to take drugs without authorization, to prevent induced heart disease. In addition, usually to maintain a relaxed mood, avoid anger, avoid excessive stress, to quit smoking and limit alcohol, eat less salty meat, fried chicken and other high salt and high sugar food.