1.Posterior sternal or precordial pain, or tightness-like pain, radiating to the left shoulder and left upper arm, lasting 3-5 minutes, occurs during exertion or mental tension. 2, Chest tightness, palpitation and shortness of breath appear with physical activity and are relieved after rest. 3.The appearance of exercise-related headache, toothache, leg pain. 4.Chest pain and palpitations when full, cold or watching thrillers. 5.Sleeping requires high pillow position; sudden chest pain, palpitations and difficulty in breathing when lying down, which can be relieved by sitting up or standing up immediately. 6.Discomfort such as panic and chest tightness when having sex or having difficulty in defecation. 7.Hearing noise with heart panic and chest tightness. 8.Recurring irregular pulse, unexplained tachycardia or bradycardia.