When vaginal blisters appear, they may be genital herpes, vaginal radioactive injury, etc. They need to be promptly identified and treated as soon as possible based on other signs and tests. Common causes and treatment 1. Genital herpes: vaginal infection with the herpes virus, usually small blisters that show aggregation and ulcerated wounds with pain at the rupture of the blisters, usually with antiviral drugs such as acyclovir. 2. Vaginal radiation damage: usually caused by radiation therapy in patients with malignant tumors. Patients may feel vaginal dryness and pain, and during gynecological examination, flushing or small blisters of vaginal mucosa are found, and in severe cases, vaginal tissue ulceration occurs. Depending on the patient’s condition, the doctor should choose an appropriate treatment method, such as medication. It is not advisable to have intercourse during the treatment of vaginal blisters to prevent aggravation of the disease. Also, pay attention to nutrition, adjust the diet structure and eat high protein food to enhance the body’s ability to resist disease.