Mr. Li recently had paroxysmal involuntary fluttering of his left eyelid, which worsened when he was tired and tense, and reduced when he rested and relaxed. He thought he was too tired recently and would be fine after a while, but half a month later the eyelid fluttering became more and more pronounced, and even his right eye started to flutter. In the past three months, Auntie Wang was found by her family to be blinking all the time, and the blinking would get worse when she was nervous and lessen when she relaxed. When watching TV or walking in the street when the sun is bright, her eyes are uncomfortable and it is hard to open them, and they are dry. After going to the ophthalmology department for related examinations, the doctor initially diagnosed “dry eye” / “keratitis”, but the effect of using eye drops was not obvious. The final diagnosis for both of these patients was blepharospasm. Blepharospasm is an unexplained, involuntary spasm and twitching of the muscles in the innervated area of the facial nerve that occurs in middle-aged and elderly people and causes great physical pain and aesthetic discomfort. The duration of the spasm can be long or short, and the spasm is manifested by the constant repetition of involuntary strong eye closures. Many patients with blepharospasm have endured considerable pain for a long time before receiving a definitive diagnosis and treatment, and timely treatment is often delayed due to misdiagnosis.