1. Clean your hands before using the medication, tilt your head back, look upward, gently connect your lower eyelid with a cotton swab or index finger downward to expose the conjunctival sac below, and put the drops into the conjunctival sac below. You should not put too many drops at a time to avoid wasting the solution. 2. Close your eyes gently for about 1 minute after the drops to prevent the drops from spilling out. If there is any outflow of medication, wipe it off with a cotton pad or paper towel. 3.When applying drops to both eyes, first apply to the healthy eye and then to the diseased eye. Do not let the mouth of the eye drops touch the eye to avoid contamination of the drops.