The symptoms of headache and nausea appear in the middle of the night: first of all, we should exclude whether the patient is suffering from acute cerebrovascular disease. In addition, it is likely that the patient has consumed suspicious spoiled food before going to bed, and when sleeping in the middle of the night, the suspicious spoiled food will have a certain reaction on the body and the symptoms of headache and nausea will appear. In addition, the patient should consider whether the migraine attack is triggered by excessive stress and strain due to the stressful work during the day. In addition, patients should also have their blood pressure measured as well as blood tests to carefully look for the cause of the headache and nausea.