When friends and relatives get together during Chinese New Year holidays, it is inevitable to have a few drinks to enhance the relationship and enliven the atmosphere. In ancient China, there are good stories related to wine, such as “a thousand cups of wine is less than a thousand cups of wine for a friend who understands you” and “what can be done to relieve worries, only Dukang”. However, drinking alcohol should be based on the specific conditions of individuals, moderate, avoid excessive, otherwise it will cause harm to the body. Alcohol decomposition and metabolism is almost entirely carried out in the liver, through the role of enzymes, from ethanol into acetaldehyde, and then from acetaldehyde into acetic acid, and ultimately absorbed by the body. Drinking alcohol in moderation will not cause significant harm to the body. The metabolic capacity of alcohol tolerated by the liver of a normal person is about 1 gram per kilogram of body weight per day, and a person weighing 60 kilograms should be limited to less than 60 grams of alcohol per day of permissible intake. However, each person’s tolerance to alcohol is related to genetic factors, and people who are allergic to alcohol can have serious adverse reactions or even life-threatening effects even if they drink a small amount of alcohol. A small amount of wine is good for cardiovascular health. Li Shizhen in the Ming Dynasty wrote in the Compendium of Materia Medica that wine has the effect of “warming the waist and kidneys, maintaining color, and resisting cold”. Excessive drinking can lead to alcoholic liver disease (alcoholic fatty liver, alcoholic hepatitis, alcoholic cirrhosis), gastric hemorrhage, pancreatitis, etc. Alcohol poisoning can be life-threatening. Alcohol can affect male reproductive function and can cause intellectual developmental disorders in offspring. Chinese medicine believes that alcohol is sweet and warm in nature, long-term or excessive drinking can lead to dampness and heat in the body. Dampness and heat can cause loss of appetite, nausea and vomiting, fatigue, etc., and in severe cases, jaundice and dropsy can occur. The following categories of people should not drink more alcohol or should be absolutely abstain from alcohol: 1, hypertension, cardiovascular and cerebrovascular disease patients: alcohol can make the brain excitation, emotional excitement, vasodilatation, induced by increased blood pressure, arrhythmia, rapid heartbeat and other undesirable symptoms, serious vascular spasm, acute infarction, or vascular rupture, cerebral hemorrhage or even sudden death. 2, patients with liver disease should absolutely abstain from alcohol. More than 95% of the alcohol ingested into the body is metabolized by the liver, and the metabolic function of the liver itself is poorer than that of a normal person with liver disease, and if you drink again, it will lead to aggravation of the condition and even accidents. 3, patients with gastrointestinal diseases: alcohol stimulates the gastric mucosa, excessive drinking can cause indigestion, gastritis, gastric bleeding. Patients suffering from gastric ulcer, gastritis, enteritis and other diseases should not drink alcohol, and people with hemorrhoids should not drink alcohol. If you must drink, you should try to eat some dishes or food first, do not drink on an empty stomach. 4, diabetic patients: drinking alcohol can cause sugar metabolism disorders, resulting in damage to the function of the pancreatic islets, causing elevated glucose concentration in the blood, aggravating the symptoms of diabetes. 5, snoring people: sleep snorers upper airway narrowing, alcohol after drinking to sleep on the upper respiratory tract muscles have a direct paralyzing and relaxing effect, serious upper airway obstruction will occur, frequent sleep apnea phenomenon. After drinking a lot of alcohol, the brain’s arousal response to asphyxia hypoxia becomes sluggish, and the duration of asphyxia is prolonged, especially in the second half of the night will be more serious, and sudden death in sleep may occur as a result. 6, female drinking harm: drinking alcohol to increase the chance of menopausal women suffering from breast cancer, pregnant women drink too much alcohol, may make the baby deformed, mental retardation, and even fetal death. Patients who are taking medication should be aware that certain medications taken at the same time as alcohol can cause serious problems, even life-threatening. (1) Alcohol and tranquilizers: Both alcohol and sleeping pills can produce strong cerebral nerve inhibition, and patients are therefore prone to coma or death by poisoning. (2) Alcohol and hypoglycemic drugs: Drinking alcohol while injecting insulin or taking oral hypoglycemic drugs is prone to hypoglycemic reactions. Such hypoglycemic symptoms (panic, sweating, fatigue and weakness, or even irritability, confusion, and verbosity) are not easy to distinguish from drunkenness, and can often lead to hypoglycemic shock if not handled properly. If not treated in time, it may lead to irreversible damage to brain tissue and even cause death. (3) Alcohol and aspirin: Aspirin is highly irritating to the gastric mucosa, easily causing gastrointestinal bleeding. Drinking alcohol while taking medication will aggravate the adverse drug reaction and cause gastrointestinal hemorrhage. (4) Alcohol and antihypertensive drugs: alcohol dilates blood vessels, thus enhancing the antihypertensive effect of drugs, therefore, it is easy to take antihypertensive drugs after drinking alcohol hypotension, and in severe cases, it may even cause sudden death. (5) Alcohol and cephalosporin antibiotics: can lead to serious alcohol poisoning. Cephalosporin antibiotics will inhibit the metabolism of alcohol in the body, resulting in the accumulation of alcohol in the body, damage to the liver, kidneys and heart and other organs, causing a toxic reaction of the body, even if a small amount of alcohol mixed with such drugs may lead to toxicity, nausea and vomiting, abdominal pain, headache and even respiratory difficulties and other symptoms. So how to avoid intoxication? First of all, alcohol intake should be minimized, which is the first condition to avoid drunkenness; secondly, drink some milk and eat some fruits in moderation before drinking, eat more meat, bean curd and eggs when drinking, try to avoid drinking on an empty stomach to slow down the absorption of alcohol; people in poor physical condition or taking medication should be prohibited from drinking alcohol. After drunkenness, some people take to drink strong tea, vinegar, coffee and other methods to solve the problem, in fact, this is not the correct way to solve the problem. Tea contains theophylline and caffeine, which have an excitatory effect and increase the burden on the heart. Drinking strong tea after drunkenness, the theophylline in tea will quickly pass through the kidneys to produce a strong diuretic effect, the alcohol in the body will not be decomposed when the premature entry into the kidneys, harmful to human health. Drinking vinegar can cause nausea and vomiting, and in severe cases, upper gastrointestinal bleeding. Coffee stimulates vasodilatation, accelerates blood circulation, increases cardiovascular burden, and can be seriously life-threatening. The correct way to relieve alcohol is to give the drunken person some fruit or drink fruit juice, tomato juice or soup, ginger soup, vegetable soup, rice soup, honey water, yogurt, etc., or use Chinese medicine to relieve alcohol. The Chinese medicine Pueraria Mirifica is good at detoxifying alcohol, waking up the spleen and stomach, and quenching thirst, and is mainly used for treating excessive drinking, headache and dizziness, thirst and vomiting, and fullness in the chest and diaphragm. The common use of Pueraria Mirifica with red dates in decoction soup, has a very good effect on alcohol detoxification. In addition, Pueraria Mirifica, Herba Fructus, Gaultheria, Bitter Ginseng, Chrysanthemum, Bupleurum, Nutmeg and other traditional Chinese medicines also have the effect of sobriety. If serious alcohol poisoning occurs, should be sent to the hospital for rescue.