Epiphyseal closure is mostly judged by age and X-ray examination results, in the following ways: 1. Age: During the normal growth and development of the body, as age increases, the epiphysis will gradually calcify until it is completely ossified, that is, the epiphyseal closure is completed. This physiological closure is mainly seen in adolescence, with male bone age at about 18 years old and female bone age at about 17 years old. Generally, the epiphysis of the lower extremity closes later than the epiphysis of the upper extremity, and the epiphysis of males closes later than the epiphysis of females; 2. X-rays: The state of the epiphysis can be clearly seen on X-rays, and usually the most important locations to check are the knee and ankle joints, where the epiphysis is related to the main height changes. x-rays that show a wide translucent band indicate that the epiphysis has not yet closed. With age, when the cartilage at the epiphysis and epiphysis ends is completely ossified, the epiphysis line at both ends of the long bones is seen to disappear and a tight seam is formed, then the epiphysis line can be judged to be closed. If premature epiphyseal closure is caused by fractures, tumors, and other factors, the differential diagnosis can also be made by x-ray examination.