Urticaria can usually be cured, some patients may experience chronicity and recurrent attacks. Urticaria occurs in people with allergies and can be affected by drugs, food, respiratory inhalants, physical factors, mental and infectious factors. Since it is difficult to identify the cause of the disease, and will reoccur after exposure to allergens, it is easy to recur and usually difficult to cure. Acute urticaria can cause laryngeal edema or even asphyxiation in severe cases, which should be detached from the allergic substances as soon as possible, and should be treated by medical first aid, and first aid medications should be selected according to the situation, such as hormonal medications like 0.1% adrenocorticotropic hormone, methylprednisolone, prednisone, etc., and cricothyrotoxic puncture can be carried out if necessary. Chronic urticaria patients can follow the doctor’s instructions to use fexofenadine, avastin, benadryl and other antihistamines, with prednisone, ranitidine, montelukast and other drugs. Severe itching can be used externally with glycerine lotion, benadryl cream and so on. Urticaria patients can consult a doctor in time for examination and treatment, which can control the development of the disease.