There is no way to cure premature ejaculation with dapoxetine hydrochloride tablets. The mechanism of this medication for premature ejaculation is complicated and may be related to the inhibition of neuronal reuptake of 5-hydroxytryptamine, that is, the enhancement of 5-hydroxytryptamine neurotransmitter in the prominent gap, or it may be that ejaculation is mainly mediated by the sympathetic nervous system and the medication can act on the sympathetic nerves at the upper level of the spinal cord and inhibit the reflexes driven by the ejaculatory center to delay the This can be used to treat premature ejaculation. However, drugs that act on the central nervous system can be effective for some people after a period of time, but the effectiveness of others will slowly decrease. Premature ejaculation is a very complex factor, which may be both organic and psychological, so it is difficult to expect to cure premature ejaculation with dapoxetine.