Usually normal adults urinate 0-2 times at night, and an increase in the number of urination per unit time is frequent urination. Physiological conditions such as drinking a lot of water, beer or eating watermelon at night before going to bed can cause frequent nocturnal urination. In addition, it can also be seen in some pathological conditions, need to consider whether it is accompanied by an increase in the number of urination during the day, changes in urine volume and other accompanying symptoms, etc., should not blindly use drugs, it is recommended to first consult a doctor to determine the cause: 1, bladder disease: clinical mostly seen in acute cystitis and other causes of urinary tract infections, as well as overactive bladder disease, etc., patients can appear frequent nocturia, mostly accompanied by urinary urgency, painful urination performance, need to take antibiotic treatment, such as The patient should take antibiotics such as cephalosporin, amoxicillin, etc.; 2, prostate disease: such as prostatitis, prostate hyperplasia, etc. Prostatitis needs to be treated with drugs according to the specific condition, clinical use of cephalosporin, azithromycin, ciprofloxacin and other antibacterial drugs, as well as celecoxib, tamsulosin hydrochloride and other drugs for treatment; for patients with prostate hyperplasia, clinical use of doxazosin, finasteride and other drugs for treatment, if necessary If necessary, surgical treatment is also available; 3. Enuresis: It is mostly seen in children and may be caused by genetics, fright, urethral abnormalities and developmental delay, etc. Behavioral and pharmacological interventions are needed, such as limiting the amount of water drunk before bedtime and urinating before going to bed. Renal tubular concentration dysfunction, etc., need to be treated for the cause, clinical use of ciprofloxacin, amoxicillin, furosemide, calcium carbonate, nifedipine, etc.; 5, heart disease: such as heart failure, increased cardiac blood return at night when lying down, increased renal blood perfusion, while atrial antidiuretic hormone secretion increased, resulting in increased renal filtration rate, frequent nocturia. Patients need long-term treatment, diuretics, angiotensin-converting enzyme inhibitors such as captopril, and nitrates, beta-blockers, positive inotropic drugs, etc. can be applied for treatment, and specific medications need to follow medical advice; 6. Other: frequent nocturia can also occur, such as uremia, psychogenic polyhydramnios, diabetes mellitus, etc. The frequent nocturnal urination caused by diabetes can be treated with oral metformin, glimepiride, etc. under the guidance of doctors, and if necessary, insulin can be injected.