One cell divides and proliferates over roughly 30 cell cycles to reach roughly 109 and a size of a few millimeters. Therefore, malignant tumors are not the result of a single day, and the evolution from cancerous transformation of a single cell to a malignant systemic disease is bound to undergo a considerable period of time. During this period of time when the tumor is gradually increasing in size, whether it is the volume factor that stimulates the surrounding tissues or cells, or the secretion factor that leads to the dysfunction of normal tissues or cells, or apoptosis and the emergence of the body’s repair mechanism, some concomitant symptoms, such as cough and coughing up blood, blood in the stool, hematuria, and so on, may appear. These symptoms do not seem to have any specificity and are often easily ignored. However, if early examination and treatment are carried out according to these symptoms, the tumor can often be eliminated at the earliest stage in order to obtain the best prognosis. These symptoms sometimes occur by themselves, and sometimes we need to develop some good habits. Cough is one of the most common symptoms in our life. Whether it is chronic pharyngitis, common cold or serious respiratory diseases, cough may be the most dominant symptom, and therefore it is most easily neglected by us. Due to the influence of air pollution, smoking and bad living habits, the incidence of lung cancer is increasing year by year all over the world, and cough is one of the most common and earliest symptoms of lung cancer. How can we distinguish ordinary cough from cough caused by lung cancer? Firstly, from the point of view of appearance and duration: general cough often has triggering causes, such as upper respiratory tract infection, lung infection, etc., when the primary disease is controlled, the cough symptoms will be gradually reduced or disappeared; whereas the cough caused by lung cancer often does not have any triggering causes or seizure phases, has a long course of disease, the symptoms are not easy to be improved, and is poorly sensitive to the medicines for suppressing cough. Secondly, from the point of view of the nature of cough: general cough is often accompanied by fever, sore throat, coughing up sputum, etc., while cough caused by lung cancer is most common as irritating dry cough, which is due to the fact that the tumor tissue invades the airway during the process of growth, triggering the symptoms of airway irritation and the emergence of irritating dry cough, which is often not accompanied by coughing up sputum, sore throat, etc., such as blood sputum can be seen when the tumor grows and causes the rupture of the local capillaries. Therefore, if there is no obvious cause and no obvious improvement of irritating dry cough after treatment, one should go to the referral doctor for examination in time. Blood in stool is also the most common clinical symptom in life, mainly seen in hemorrhoids, intestinal inflammation, gastrointestinal malignant tumors and so on. If subdivided, blood in stool can be subdivided into blood on the surface of feces, blood in feces, blood at the beginning of feces without obvious blood, blood in the whole bowel movement, and so on. Hemorrhoidal bleeding is mainly manifested as fresh blood on the surface of feces, which is due to the friction when feces passes through the anorectum and occupies fresh blood on the surface; purely with fresh blood at the beginning of defecation, if combined with the hardness of feces which is difficult to be eliminated, it is considered to be the process of defecation because of the hardness of feces which damages the local intestinal mucous membranes and leads to bleeding. Blood in stool caused by digestive tract tumors usually lasts for a long time, and the form of blood in stool is variable, and changes in bowel movement pattern and stool texture are common. If you find irregular blood in stool, carefully observe which of the above forms of blood in stool you are having, and then communicate with your doctor in detail with your own medical history, so that you can have a variety of tests such as finger-pointing or colonoscopy to clarify the nature of the lesion in time, so that you can find it at an early stage and have it treated at an early stage. Of course, a variety of malignant tumors can be bleeding as the main manifestation, blood in the stool is only one of them. Hematuria is also very common in clinic, for example, we should pay attention to observe whether it is hematuria at the beginning, middle and end or the whole process, which can be seen in many kinds of malignant neoplastic diseases of the urinary system, such as renal cancer, bladder cancer, ureteral malignant tumor and so on, and the further examination can make clear those parts of the lesion. Epistaxis is mostly seen in adolescents, but also in middle-aged and old people, if it occurs frequently without any triggering factors, then we should beware of it, and we must exclude nasopharyngeal carcinoma. Coughing and hemoptysis or blood in sputum, as we have mentioned above, should be excluded as lung cancer. In addition to paying attention to the clinical symptoms mentioned above, one should also observe carefully whether there is pain without obvious reasons, lumps, weight loss or emaciation, fatigue and tiredness, etc. According to the symptoms, targeted examination will lead to early detection of malignant tumors. In addition to passively waiting for clinical symptoms to “come to the door”, we can also develop a few good habits, take the initiative! The first is breast self-examination. In developed countries, the incidence rate of breast cancer is significantly higher than that of other malignant tumors, which is closely related to the modern dietary structure and lifestyle changes. The prognosis of breast cancer is relatively good after early diagnosis and treatment, so early detection and diagnosis are more important for breast cancer patients. In fact, it is not difficult to detect breast cancer at an early stage, only regular self-examination is needed to detect its traces at an early stage. The easiest way is to observe in the mirror when taking a shower, to see whether both breasts are symmetrical in shape, whether there is any “orange peel” change in the surface skin, and whether there is any abnormal change in the areola, etc.; and then to carry out the palpation, you can use the end of the four fingers to carry out self-touching in accordance with a fixed direction, to see whether there is any lump or nodule. Breast self-examination can be performed once every menstrual cycle, which is simple, convenient and significant! Lymph node palpation is also important for the self-discovery of malignant tumors. Lymph nodes are widely distributed in many parts of the body, among which the most easily palpable and commonly used superficial lymph nodes are bilateral submandibular, anterior and posterior neck, upper and lower clavicle, armpit and groin. Lymph nodes can be palpated once a month, with attention paid to mobility and tenderness. If lymph nodes are found to be enlarged, systematic examination according to the area in which they appear can be of great help in the early detection of malignant tumors.